Altered Expression of Neurotransmitter Receptors and Neuromediators in Vernal Keratoconjunctivitis
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چکیده
منابع مشابه
Expression of chemokine receptors in vernal keratoconjunctivitis.
BACKGROUND/AIMS Chemokines are small peptides which are potent activators and chemoattractants for leucocyte subpopulations. Their action is mediated by a family of seven transmembrane spanning G-protein coupled receptors. The aims of this study were to examine the expression of the chemokine receptors CCR1, CCR3, CCR5, CXCR3, and CXCR4 in the conjunctiva of patients with vernal keratoconjuncti...
متن کاملVernal keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a chronic allergic conjunctivitis that is most often seen in young, males. Although most types of allergic conjunctivitis do not affect vision, VKC is unusual in that damage to the cornea from the condition can result in vision loss. Although it is typically seasonal, year-round symptoms can be seen, which can lead to uncertain diagnoses being made. Although...
متن کاملManagement of Vernal Keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a relatively rare, chronic form of ocular allergy that can potentially cause severe visual complications. Affecting mainly children and young adults, it is an IgE- and T cell-mediated disease, leading to a chronic inflammation in which eosinophil, lymphocyte and structural cell activation are involved. Treatment of VKC requires a multiple approach that inclu...
متن کاملAdhesion molecules in vernal keratoconjunctivitis.
AIMS/BACKGROUND Adhesion molecules play a key role in the selective recruitment of different leucocyte population to inflammatory sites. The purpose of the present study was to investigate the presence and distribution of adhesion molecules in the conjunctiva of patients with vernal keratoconjunctivitis (VKC). METHODS The presence and distribution of adhesion molecules were studied in 14 conj...
متن کاملGelatinase B in vernal keratoconjunctivitis.
OBJECTIVES To investigate the expression of gelatinase B in the conjunctiva of patients with vernal keratoconjunctivitis (VKC) and the cellular source of this enzyme. METHODS Conjunctival biopsy specimens from 12 patients with active VKC and 12 control subjects were studied using immunohistochemical techniques and a monoclonal antibody against gelatinase B. The phenotype of gelatinase B(+) in...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2006
ISSN: 0003-9950
DOI: 10.1001/archopht.124.4.462